The role of T helper 9(Th9) against Infectious Diseases

Mehdi Agha Seyed Hosseini; Amir Hossein Mansourabadi; Ali Shams; Nastaran Razavi; Reza Daryabor; Mohammad Hasan Zadeh

Volume 2, Issue 4 , November 2015, , Pages 233-238

  Background and aims: Infectious diseases are disorders caused by organisms such as bacteria, viruses, fungi or parasites .The Th9 subset develops in response to combined signals from TGF-b and IL-4 among a cacophony of other cytokines in an extracellular milieu. T helper 9 (Th9) cells,  as a novel ...  Read More

Infectious Disease
The Role of Interleukin (IL-22) in immune response to human diseases

Mehdi Agha Seyed Hosseini; Amir hossein Mansourabadi; Ali Shams; Nastaran Razavi; Mohammad Hassanzadeh

Volume 2, Issue 3 , September 2015, , Pages 152-161

  Background and aims: IL-22 is an alpha- helical cytokine. IL-22 binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1subunits. IL-22R is expressed on tissue cells, and it is absent on immune cells. L-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction ...  Read More